AMSM - Chris Boesch - Curriculum Vitae

 

Magnetic Resonance Spectroscopy and Methodology - Department of Clinical Research - University Bern/Switzerland

 

Chris Boesch, MD & PhD

Professor and Head of AMSM

 

 

Education and Positions


      1976 Physics Diploma (Dipl.Phys.ETH), Eidgenössische Technische Hochschule (Federal Institute of Technology), Zurich

      1980 PhD in Physics (Dr.sc.nat.), Eidgenössische Technische Hochschule (Federal Institute of Technology), Zurich, Institut für Molekularbiologie und Biophysik, Prof.Kurt Wüthrich. Title of thesis: "Bösch, C. Konformationsstudien am Polypeptidhormon Glucagon mittels hochauflösender Kernresonanzspektroskopie in wässriger Lösung und an einer hydrophob/hydrophilen Grenzfläche. (Studies on the conformation of the polypeptide-hormone glucagon using high-resolution nuclear magnetic resonance in aqueous solution and in a hydrophobic-hydrophilic interface.). 

      1984 Swiss State License for Medicine, University of Zurich, Switzerland

      1985 MD (Dr.med.), University of Zurich, Switzerland, Prof. G.Duc, Title of thesis: "Boesch, C. Medizinisch-physikalische Überlegungen bei Evaluation und Installation eines Hochfeld-NMR-Tomographen in Pädiatrie und Neonatologie. (Medical and physical considerations during evaluation and installation of a high-field-NMR tomographic system in pediatrics and neonatology.)"

      1985-1990 Research Assistant University Children's Hospital in Zurich Switzerland, (Dr.E.Martin)

      1991- ... Professor of Magnetic Resonance Spectroscopy and Methodology at the University of Bern, Switzerland

      2006 Visiting professor at the Université Claude Bernard Lyon 1, France

      2006 Distinguished Service Medal and Fellow of ISMRM

      2006 Fellowship of ESMRMB

      2008-2013 President of the Research Commission, University of Bern, Switzerland

      2013- .... Member of the National Research Council (Swiss National Science Foundation)

 

 

Scientific Functions


 

      1992 - 1995 : Treasurer ESMRMB

      1996 : Chairman Scientific Program Committee (ESMRMB Annual Meeting, Prague 1996)

      1996 - 1997 : Vice-President ESMRMB

      1996 - 1999 : Board of Trustees ISMRM

      1997 - 1998 : President ESMRMB

      1998 : Chairman Scientific Program Committee (ISMRM Annual Meeting, Sydney 1998)

      1998 - 1999 : Immediate Past President ESMRMB

      1999 - 2000 : Vice-President ISMRM

      2000 - 2001 : President-Elect ISMRM

      2001 - 2002 : President ISMRM

      2002 - 2003 : Immediate Past President ISMRM

 

 

Editorial and Reviewer Functions


 

      NMR in Biomedicine (Review Editor)

      Magnetic Resonance in Medicine (Editorial Board 1998-2004)

      Journal of Magnetic Resonance Imaging (Associate Editor)

      MAGMA (Editorial Board 2000-2005)

      Radiology (Reviewer)

      ISMRM - International Society for Magnetic Resonance in Medicine (Reviewer)

      ESMRMB - European Society for Magnetic Resonance in Medicine and Biology (Reviewer)

      Reviewer for a series of other journals on a case-to-case basis

 

 

Grants, Swiss National Science Foundation


 

      2013 – 2016       Principal Investigator of Swiss National Science Foundation project (#310030-149779): “Multi-nuclear magnetic resonance spectroscopy (MRS) and imaging (MRI) on a clinical whole-body MR-system: Lipid organelles and mitochondria “ (PI C.Boesch, CI L.Tappy, CI E.Christ, CI J.-F.Dufour, CI R.Kreis)

      2014 – 2017       Co-Investigator of Swiss National Science Foundation project (#320030-149321): “Exercise-related Fuel Metabolism and Glucose Stability in Individuals with Type 1 Diabetes Mellitus.” (PI C.Stettler, CI C.Boesch, CI M.Wilhelm, CI L.Tappy)

      2011 – 2014       Co-Investigator of Swiss National Science Foundation project (#320030-138428): “Modulation of fructose’s metabolic effects by environmental factors.” (PI L.Tappy, CI C.Boesch, CI R.Kreis)

      2011 – 2014       Co-Investigator of Swiss National Science Foundation project (#320030-138150): “Advanced multi-modal MR Imaging and Spectroscopy for Comprehensive Characterization of Renal Function in Native and Transplanted Kidneys“ (PI P.Vermathen, CI U.Eisenberger, CI C.Boesch)

      2011 – 2014       Co-Investigator of Swiss National Science Foundation project (#320030-135743): “Magnetic Resonance Techniques to Investigate Human Brain Physiology: Acquisition and Postprocessing Tools to Advance Spectroscopy at Clinical and High Magnetic Fields” (PI R.Kreis, CI C.Boesch, CI K.Pruessmann)

      2011 - 2013        Co-Investigator of Swiss National Science Foundation project (#320030-135782): “Effects of a reduction in sweetened beverage consumption on cardio-metabolic risk factors and food intake in overweight subjects.” (PI L.Tappy, CI V.Giusti, CI C.Boesch).

      2010 – 2013       Principal Investigator of Swiss National Science Foundation project (#31003A-132935): “Multi-nuclear magnetic resonance spectroscopy (MRS) and imaging (MRI) on a clinical whole-body MR-system: insulin resistance, ageing, and physical activity“ (PI C.Bösch, CI L.Tappy, CI E.Christ, CI J.-F.Dufour, CI R.Kreis)

      2010 - 2013        Co-Investigator of Swiss National Science Foundation project (#320030-130331): “The effect of dietary fat load and physical exercise on the flexibility and partitioning of ectopic lipids (intramyocellular, intrahepatocellular, intramyocardial lipids)” (PI E.Christ, CI C.Stettler, CI C.Bösch)

      2009 - 2011        Co-Investigator of Swiss National Science Foundation project (R’Equip #206021-128736): “High Resolution Magic Angle Spinning (HR-MAS) probe for NMR spectroscopic investigations of semi-solid liquid-like materials” (PI M.Vermathen, CI P.Bigler, CI C.Boesch, CI P.Vermathen)

      2008 - 2011       Co-Investigator of Swiss National Science Foundation project (#310030-121995): “Metabolic effects of dietary proteins in insulin resistance “ (PI L.Tappy, CI C.Boesch, CI V.Giusti)

      2008 - 2011       Co-Investigator of Swiss National Science Foundation project (#320000-120324): “Magnetic Resonance Techniques to Investigate Human Brain Physiology: Novel Acquisition and Processing Methods to Extend the Scope and Robustness of Clinical Spectroscopy at High Magnetic Fields"” (PI R.Kreis, CI C.Boesch, CI P.Bösiger)

      2007 - 2010       Principal Investigator of Swiss National Science Foundation project (#310000-118219): “Multi-nuclear magnetic resonance spectroscopy (MRS) and imaging (MRI) on a clinical whole-body MR-system: integration and application of the MR-toolbox for studies on insulin resistance“ (PI C.Bösch, CI R.Kreis, CI L.Tappy, CI E.Christ)

      2006 – 2009      Co-Investigator of Swiss National Science Foundation project (#320000-113512): “Noninvasive Detection of Clinically Occult Lymph Node Metastases in Prostate and Bladder Cancer Evaluated by USPIO-Enhanced MRI and Diffusion-Weighted MRI: a Histopathologic Correlation” (PI H.C.Thoeny, CI U.E.Studer, CI A.Fleischmann, CI P.Vermathen, CI C.Boesch)

      2005 - 2008       Co-Investigator of Swiss National Science Foundation project (#310000-109737): “Environmental and genetic factors in the development of hepatic and extrahepatic insulin resistance in humans“ (PI L.Tappy, CI C.Boesch, CI T.Bernard)

      2006 - 2009       Co-Investigator of Swiss National Science Foundation project (#320000-109522): “The effect of growth hormone (GH) on intramyocellular (IMCL), intrahepatic lipids (IHCL) and visceral fat mass in relation to insulin resistance“ (PI E.R.Christ, CI C.Boesch, CI P.Diem, CI C.Stettler)

      2005 - 2008       Co-Investigator of Swiss National Science Foundation project (#320000-108321): “Localization of synchronized brain activity using combined EEG and fMRI“ (PI T.König, CI C.Boesch, CI T.Dierks)

      2004 - 2007       Principal Investigator of Swiss National Science Foundation project (#3100A0-105815): “Multi-nuclear magnetic resonance spectroscopy (MRS) and imaging (MRI) on a clinical whole-body MR-system: non-invasive observation of metabolism in healthy and diabetic skeletal muscle and liver tissue“ (PI C.Bösch, CI R.Kreis, CI L.Tappy, CI H.Hoppeler, CI E.Christ)

      2004 - 2009       Co-Investigator of Swiss National Science Foundation project (NFP53 #405340-104531): “Whiplash: New Aspects and Detailed MR Imaging with Therapeutic and Preventative Measures” (PI S.Anderson, CI C.Boesch, CI A.Busato, CI M.Curatolo, CI J.Hodler, CI A.Nidecker, CI M.Sturzenegger, CI H.Zimmermann)

      2004 - 2007       Co-Investigator of Swiss National Science Foundation project (#3100A0-103938): “Quantitative Magnetic Resonance Techniques to Investigate the Human Brain: Novel Methodology and Studies Probing the Blood Brain Barrier” (PI R.Kreis, CI C.Bösch, CI J-M.Nuoffer)

      2003 - 2006       Co-Investigator of Swiss National Science Foundation project (#3200BO-100146): “Effects of growth hormone on skeletal muscle fuel metabolism“ (PI E.Christ, CI C.Bösch, CI P.Diem, CI M.Flück)

      2001 - 2004       Principal Investigator of Swiss National Science Foundation project (#3100-065315): “Multi-nuclear magnetic resonance spectroscopy (MRS) and imaging (MRI) on a clinical whole-body MR-system: Integrated, non-invasive analysis of metabolism and function of human skeletal muscle“ (PI C.Bösch, CI L.Tappy, CI R.Kreis, CI H.Hoppeler)

      2001 - 2004       Co-Investigator of Swiss National Science Foundation project (#31-65276): “Skeletal muscle plasticity: The contribution of the transcriptome to adaptations induced by mechanical activity and hypoxia” (PI M.Flück, CI H.Hoppeler, CI M.Vogt, CI C.Boesch)

      2000 - 2003       Co-Investigator of Swiss National Science Foundation project (#3100-059082): “Quantitative magnetic resonance spectroscopy in the human brain: methodology and clinical applications” (PI R.Kreis, CI C.Bösch, CI M.Steinlin, CI K.O.Loevblad)

      1998 - 2001       Co-Investigator of Swiss National Science Foundation project (#3100-054045): “The molecular basis of functional and structural plasticity of human skeletal muscle tissue” (PI H.Hoppeler, CI R.Billeter, CI C.Boesch)

      1998 - 2001       Principal Investigator of Swiss National Science Foundation project (#3100-053788): “Multi-nuclear magnetic resonance spectroscopy (MRS) on a clinical whole-body MR-system: In vivo analysis of energy metabolism and ordered biological structures“ (PI C.Bösch, CI H.Hoppeler, CI R.Kreis)

      1995 - 1998       Co-Investigator of Swiss National Science Foundation project (#32-43426): “Postnatal brain development: The neonatal period." (PI E.Bossi, CI P.Hueppi, CI C.Boesch, CI G.Schroth)

      1996 - 1999       Co-Investigator of Swiss National Science Foundation project (#3100-043280): “Optimization of quantitative clinical magnetic resonance spectroscopy and application to chronic hepatic encephalopathy” (PI R.Kreis, CI C.Bösch)

      1995 - 1998       Principal Investigator of Swiss National Science Foundation project (#3100-042162): “Multi-nuclear magnetic resonance spectroscopy (MRS) on a clinical whole-body MR-system: Assessment of energy metabolism and potential for conformation analysis in vivo“ (PI C.Bösch, CI H.Hoppeler, CI R.Kreis)

      1992 - 1995       Principal Investigator of Swiss National Science Foundation project (#3100-030971): “Multi-nuclear magnetic resonance spectroscopy (MRS) on a clinical whole-body MR-system: Characterization of oxidative capacity and glycogen content of human muscle“ (PI C.Bösch, CI H.Hoppeler)

      1991 - 1994       Co-Investigator of Swiss National Science Foundation project (#31-30909): “Genetische Storungen der Myelinisierung" (PI N.Herschkowitz, CI C.Bösch, CI E.Bossi)